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THOC5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14862-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16833734

  • 325.38€ / 150µL
Expédition estimée: 03-10-2022
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Description

Description

Component the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5′ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi′s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction beteen KSHV ORF57 protein and THOC4. UAP56 functions as a bridge between THOC4 and the THO complex. THOC5 in conjunction with THOC4 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA. May be involved in the differentiation of granulocytes and adipocytes.
Spécification

Spécification

THOC5
Polyclonal
Unconjugated
THOC5
C22orf19, Fmip, fSAP79, hTREX90, KIAA0983, PK1.3, Placental protein 39.2, PP39.2, THO complex 5, THO complex subunit 5 homolog, THOC5
Rabbit
Antigen Affinity Chromatography
RUO
107829, 360972, 8563
-20°C
Liquid
Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry, Flow Cytometry
0.21 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q13769, Q68FX7, Q8BKT7
Thoc5
THOC5 Fusion Protein Ag6664
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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