missing translation for 'onlineSavingsMsg'
Learn More

TNFR1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 21574-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

 Afficher plus de versions de ce produit

Code produit. 16831175

  • 121.38€ / 20µL
Expédition estimée: 06-10-2022
pour voir le stock disponible 

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

TNFR1 (Tumor necrosis factor receptor 1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors. TNFR1 plays an important role in mediating, in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression. The extracellular domain of TNFR1 is also released into the circulatory system as soluble TNFR1 (sTNFR1). In humans, the TNFR1 gene is located on chromosome 12. Anti-apoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with TNFR1, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of TNFR1 were found to be associated with the autosomal domit periodic fever syndrome, and the impaired receptor clearance is thought to be a mechanism of the disease.
Spécification

Spécification

TNFR1
Polyclonal
Unconjugated
TNFRSF1A
CD120a, FPF, p55, p55 R, p60, TBP1, TBPI, TNF R, TNF R I, TNF R1, TNF R55, TNF Receptor 1, TNF Receptor I, TNF RI, TNFAR, TNFR I, TNFR1, TNFR55, TNFR60, TNFRSF1A
Rabbit
Antigen Affinity Chromatography
RUO
21937, 7132
-20°C
Liquid
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P19438, P25118
TNFRSF1A
TNFR1 Fusion Protein Ag16112
20 μL
Primary
Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
Promotions

Promotions