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TPMT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 10682-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16827223

  • 325.38€ / 150µL
Expédition estimée: 03-10-2022
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Description

Description

This antibody specifically recognizes the 34 kDa protein.

Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine. Defects in TPMT are the cause of thiopurine S-methyltransferase deficiency (TPMT deficiency). TPMT is an enzyme involved in the normal metabolic inactivation of thiopurine drugs. These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation. Patients with intermediate or no TPMT activity are at risk of toxicity after receiving standard doses of thiopurine drugs and it is shown that inter-individual differences in response to these drugs are largely determined by genetic variation at the TPMT locus.
Spécification

Spécification

TPMT
Polyclonal
Unconjugated
TPMT
Thiopurine methyltransferase, thiopurine S methyltransferase, TPMT
Rabbit
Antigen Affinity Chromatography
RUO
22017, 690050, 7172
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.15 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O55060, P51580, Q9Z0T0
TPMT
TPMT Fusion Protein Ag1074
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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