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TRIM72 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 22151-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16891685

  • 349.00€ / 150µL
Expédition estimée: 16-12-2022
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Description

Description

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.
Spécification

Spécification

TRIM72
Polyclonal
Unconjugated
TRIM72
hMG53, Mg53, Mitsugumin 53, TRIM72, tripartite motif containing 72
Rabbit
Antigen Affinity Chromatography
RUO
434246, 493829
-20°C
Liquid
Western Blot, Immunoprecipitation
0.77 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q1XH17, Q6ZMU5
Trim72
TRIM72 Fusion Protein Ag17756
150 μL
Primary
Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents

Documents

Certificats
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