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TSLP Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 13778-1-AP-20UL
Informations supplémentaires : Poids : 0.00010kg
Description
TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c (+) dendritic cells, naive CD4 (+), and CD8 (+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintece of peripheral CD4 (+) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. It is expressed in heart, liver and prostate.Spécification
TSLP | |
Polyclonal | |
Unconjugated | |
TSLP | |
thymic stromal lymphopoietin, TSLP | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
85480 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin) | |
0.13 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q969D9 | |
TSLP | |
TSLP Fusion Protein Ag4771 | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |