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von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™
Provide accurate, reproducible results with the Epredia™ von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody.
132.60€ - 670.00€
Spécification
| Antigène | von Hippel-Lindau (vHL) Protein Ab-1 |
|---|---|
| Clone | Ig33 |
| Classification | Monoclonal |
| Forme | Concentrated |
| Espèces hôtes | Mouse |
| Code produit | Marque | Quantité | Conjugué | Concentration | Prix | Quantité et disponibilité | |||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Conjugué | Concentration | Prix | Quantité et disponibilité | |||
|
12632037
|
Epredia
MS-690-B0 |
100 μL | Biotin | 200μg/mL | |||||
|
12642037
|
Epredia
MS-690-B1 |
500 μL | Biotin | 200μg/mL | |||||
|
12662037
|
Epredia
MS-690-P0 |
100 μL | Unconjugated | 200μg/mL | |||||
|
12672037
|
Epredia
MS-690-P1 |
500 μL | Unconjugated | 200μg/mL | |||||
|
12652037
|
Epredia
MS-690-P |
1 mL | Unconjugated | 200μg/mL | |||||
|
12682037
|
Epredia
MS-690-P1ABX |
100 μL | Unconjugated | 1mg/mL | |||||
|
12692037
|
Epredia
MS-690-PABX |
200 μL | Unconjugated | 1mg/mL | |||||
Description
Molecular genetic studies suggest that VHL is a tumor-suppressor gene. Alterations in the von Hippel-Lindau (VHL) gene are correlated with a diverse group of neoplasms including hemangioblastoma, clear cell renal carcinoma (RCC), and pheochromocytoma. Two transcriptional elongation factors, Elongin B and C, are shown to bind in vitro and in vivo to a short, colinear region of the VHL protein (pVHL) that is frequently mutated in human tumors. It is proposed that pVHL functions in vivo as a negative regulator of transcription elongation.Host Species: Mouse
Clone: Ig33
Isotype: IgG1/κ
Species Reactivity: Human and Mouse. Others not known.
Epitope: aa 1-54
Immunogen: A recombinant protein containing aa 1-213 of human vHL
Molecular Weight: 30kDa
Positive Control: Kidney
Cellular Localization: Cytoplasmic Ab-1 does not recognize the truncated form of VHL protein.
Note:
USA: RUO; Int'l: RUO
Spécification
| von Hippel-Lindau (vHL) Protein Ab-1 | |
| Monoclonal | |
| Mouse | |
| Cancer and Tumor Biology | |
| A recombinant protein containing aa 1-213 of human VHL | |
| Primary |
| Ig33 | |
| Concentrated | |
| RUO | |
| Human, Mouse | |
| IgG2a κ |
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