CAS RN 75747-14-7
CAS RN 75747-14-7
17-(allylamino)-17-déméthoxygeldanamycine, 99 %, Thermo Scientific Chemicals
CAS: 75747-14-7 Formule moléculaire: C31H43N3O8 Poids moléculaire (g/mol): 585.698 Numéro MDL: MFCD04973892 Clé InChI: AYUNIORJHRXIBJ-MKJFUHJFSA-N Synonyme: 17-aag CID PubChem: 133688938 Nom IUPAC: [(3S,5R,6S,7R,8Z,11R,14E)-6-hydroxy-5,11-diméthoxy-3,7,9,15-tétraméthyl-16,20,22-trioxo-21-(prop-2-énylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate SMILES: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
Tocris Bioscience™ 17-AAG
Melford 17-AAG
17-AAG (17-Allylamino-17-demethoxygeldanamycin) is a synthetic derivative of geldanamycin. Like geldanamycin, 17-AAG is recognized for its role as an inhibitor of heat shock protein 90 (Hsp90), a molecular chaperone involved in protein folding and stabilization.
17-(Allylamino) Geldanamycin, TRC
High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.
17-(Allylamino) Geldanamycin, TRC
High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.
17-(Allylamino) Geldanamycin, TRC
High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.
Tanespimycin, MedChemExpress
MedChemExpress Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression.
