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Arginase I Mouse, Unlabeled, Clone: 19, BD

Mouse Monoclonal Antibody

Marque:  BD Biosciences 610708

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15855599

  • 329.46€ / 1 kit
Expédition estimée: 15-02-2023
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Description

Description

Arginase converts arginine into urea plus ornithine, the final step in urea synthesis. Two different isoforms (I&II) have been isolated with approximately 60% homology at the nucleotide level. While type II is present in many tissues, Arginase I is expressed exclusively in liver. In cultured macrophages, as well as in vivo, Arginase I is induced with nitric oxide synthase (NOS) and the arginase I transactivator C/EBPβ in response to lipopolysaccharide. This response occurs in a dose and time-dependent manner. While the mRNA for NOS appears as early as 2h after treatment, mRNA levels for arginase I peak after twelve hours of lipopolysaccharide treatment. Since the synthesis of nitric oxide by NOS requires arginine, the delayed induction of arginase I may be necessary for the regulation of NOS activity.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Spécification

Spécification

Arginase I
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Human Arginase I aa. 53-207
50 μg
Cell Biology
Rat, Mouse, Drosophila
IgG1
Western Blot
19
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
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FDS
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For Research Use Only.