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CD152 Mouse anti-Human, PE-Cy5, Clone: BNI3, BD

Mouse Monoclonal Antibody

Marque:  BD Biosciences 555854

Informations supplémentaires : Poids : 0.02000kg

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Code produit. 15878488

  • 390.00€ / 1 pièce
Date d’expédition estimée: 14-12-2021

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Description

Description

The BNI3 monoclonal antibody specifically binds to the human cytolytic T lymphocyte-associated antigen, CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells, suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 antibody enhances T-cell proliferation induced by antibody-mediated crosslinking of CD3 and CD28. Recent studies have shown that CD152 can be expressed by regulatory T (Treg) cells. After cellular fixation and permeabilization, the BNI3 antibody can stain intracellular CD152 expressed in T cells including Treg cells. Clone BNI3.1 was studied in the VI Leukocyte Typing Workshop.

Spécification

Spécification

CD152
BNI3
CTLA-4; AILIM; Cytotoxic T-lymphocyte protein 4
Affinity Purified
Human CTLA4 Recombinant Protein
100 Tests
Immunology
Primary
Human
Flow Cytometry
PE-Cyanine5
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Mouse
IgG2a, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Vidéos
FDS
Documents
Certificats
Promotions

Promotions

For Research Use Only.