missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD152 Mouse anti-Human, PE-Cy5, Clone: BNI3, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 555854
Informations supplémentaires : Poids : 0.02000kg
Description
The BNI3 monoclonal antibody specifically binds to the human cytolytic T lymphocyte-associated antigen, CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells, suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 antibody enhances T-cell proliferation induced by antibody-mediated crosslinking of CD3 and CD28. Recent studies have shown that CD152 can be expressed by regulatory T (Treg) cells. After cellular fixation and permeabilization, the BNI3 antibody can stain intracellular CD152 expressed in T cells including Treg cells. Clone BNI3.1 was studied in the VI Leukocyte Typing Workshop.
Spécification
| CD152 | |
| Monoclonal | |
| PE-Cyanine5 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human CTLA4 Recombinant Protein | |
| 100 Tests | |
| Immunology | |
| Human | |
| IgG2a κ |
| Flow Cytometry | |
| BNI3 | |
| CTLA-4; AILIM; Cytotoxic T-lymphocyte protein 4 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.