CD3 Mouse anti-Human, PE-Cy5, Clone: UCHT1, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 561007
Informations supplémentaires : Poids : 0.01000kg
The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
For Research Use Only.