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IgD Mouse anti-Human, BB515, Clone: IA6-2, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 565243
Informations supplémentaires : Poids : 0.01000kg
Description
The IA6-2 monoclonal antibody specifically binds to the heavy chain of human Immunoglobulin D (IgD). IgD is a member of the immunoglobulin superfamily that exists in type 1-membrane (mIgD) and soluble glycoprotein forms. mIgD is expressed on mature naοve B cells (along with membrane IgM) and serves as a B-cell receptor for antigen (BCR). In response to antigen binding, the mIgD BCR, in association with other signaling molecules including CD79a and CD79b, can transduce activating or tolerizing signals intracellularly into B lymphocytes.
The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g. 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.
Spécification
| IgD | |
| Monoclonal | |
| Brilliant Blue 515 (BB515) | |
| Aqueous buffered solution containing ≤0.09% sodium azide | |
| Human IgD | |
| 100 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| IA6-2 | |
| IGHD; Ig delta chain C region; Immunoglobulin heavy constant delta | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG2a κ |
For Research Use Only.