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GTF2B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 16467-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16896094

  • 349.00€ / 150µL
Expédition estimée: 13-12-2022
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Description

Description

Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment and shuttle to the 26S proteasome is a vital means of regulating the concentrations of key regulatory proteins in the cell by limiting their lifespans. Polyubiquitination is a common feature of this modification. Serial steps for modification include the activation of ubiquitin, an ATP-dependent formation of a thioester bond between ubiquitin and the enzyme E1, transfer by transacylation of ubiquitin from E1 to the ubiquitin conjugating enzyme E2, and covalent linkage to the target protein directly by E2 or via E3 ligase enzyme. Deubiquitination enzymes also exist to reverse the marking of protein substrates. Posttranslational tagging by Ub is involved in a multitude of cellular processes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, stress responses, the immune response, and nervous system functions.
Spécification

Spécification

GTF2B
Polyclonal
Unconjugated
GTF2B
GTF2B, S300 II, TF2B, TFIIB
Rabbit
Antigen Affinity Chromatography
RUO
229906, 2959, 81673
-20°C
Liquid
Western Blot, Immunoprecipitation
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P62915, P62916, Q00403
GTF2B
GTF2B Fusion Protein Ag9547
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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