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LIN41 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 55003-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16806435

  • 329.85€ / 150µL

Expédition estimée
10-03-2021

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Description

Description

The antibody is specific to TRIM71.

TRIM71 is the mammalian ortholog to the C. elegans heterochronic protein Lin41, a protein that is thought to be important in postembryonic development, and is genetically and biochemically downstream of both Shh and Fgf signaling pathways. Similar to its C. elegans homolog, TRIM71 is a target of the microRNA let-7 and is likely to play a role in mammalian development. Recent experiments have indicated that TRIM71 is an E3 ubiquitin ligase and can interact with the Dicer and the Argonaute proteins Ago1, Ago2, and Ago4. Overexpression and depletion of TRIM71 led to inverse changes in Ago2 protein levels, suggesting TRIM71 can regulate Ago2 turnover. Finally, TRIM71 cooperates with the pluripotency factor Lin-28 in regulating let-7.
Spécification

Spécification

LIN41
0.19 mg/mL
0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
D3ZVM4, Q1PSW8, Q2Q1W2
LIN 41, LIN41, Protein lin 41 homolog, TRIM71, tripartite motif containing 71
Rabbit
IgG
150 μL
-20°C
Primary
131405, 301042, 636931
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
TRIM71
Liquid
Trim71
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Vidéos
FDS
Documents