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NLRX1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 17215-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16837064

  • 325.38€ / 150µL
Expédition estimée: 03-10-2022
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Description

Description

NLR family member X1 (NLRX1) belongs to the NLRP family and contains four LRR (leucine-rich) repeats and one NATCH domain. NLRX1 localizes to the mitochondrial outer membrane and interacts through the mitochondrial antiviral signalling adaptor MAVS during viral infection. Expression of NLRX1 results in the potent inhibition of RLH- and MAVS-mediated interferon-beta promoter activity and in the disruption of virus-induced RLH-MAVS interactions. It is also reported that NLRX1 synergistically potentiated ROS production induced by tumour necrosis factor alpha, Shigella infection and double-stranded RNA, resulting in amplified NF-kappaB-dependent and JUN amino-terminal kinases-dependent signalling, thus contributing to the link between ROS generation at the mitochondria and innate immune responses.
Spécification

Spécification

NLRX1
Polyclonal
Unconjugated
NLRX1
Caterpiller protein 11.3, CLR11.3, DLNB26, NLR family member X1, NLRX1, NOD26, NOD5, NOD9
Rabbit
Antigen Affinity Chromatography
RUO
270151, 79671
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.39 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q3TL44, Q86UT6
NLRX1
NLRX1 Fusion Protein Ag11000
150 μL
Primary
Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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