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TERF2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 22020-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1 contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types.Spécification
TERF2 | |
Polyclonal | |
Unconjugated | |
TERF2 | |
Telomeric DNA binding protein, TERF2, TRBF2, TRF2, TTAGGG repeat binding factor 2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
21750, 7014 | |
-20°C | |
Liquid |
Immunoprecipitation, Western Blot | |
0.29 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
O35144, Q15554 | |
TERF2 | |
TERF2 Fusion Protein Ag16798 | |
150 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |