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UVRAG Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 19571-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16829114

  • 325.38€ / 150µL
Expédition estimée: 06-10-2022
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Description

Description

UVRAG is predicted to contain a coiled-coil structure and is likely to be metabolically unstable based on the occurrence of a strong PEST domain. It interacts with Beclin 1, leading to activation of autophagy and thereof inhibition of tumorigenicity of human colon cancer cells. The gene for UVRAG protein is localized on human chromosome 11q13.5 and complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells. The gene has been extremely well conserved during evolution, implying an important role for this gene product in cell metabolism. Chromosomal aberrations involving this gene are associated with left-right axis malformation, and mutations in this gene have been associated with colon cancer. The protein is highly expressed in human brain, lung, kidney and liver.
Spécification

Spécification

UVRAG
Polyclonal
Unconjugated
UVRAG
DHTX, p63, UVRAG
Rabbit
Antigen Affinity Chromatography
RUO
308846, 7405, 78610
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8K245, Q9P2Y5
Uvrag
UVRAG Fusion Protein Ag13765
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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